SCHEMBL780694

SCHEMBL780694

c1ccc(-c2ccc3sc4c(-c5ccc6c(c5)c5ccccc5n6-c5ccc(-c6ccc7c8ccccc8c8ccccc8c7c6)cc5)cc(-c5ccccc5)cc4c3c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LIMK1 P53667 2/20 0.36
TSPO P30536 1/20 0.33
HDAC4 P56524 1/20 0.33
PIM3 Q86V86 2/20 0.33
ALOX5 P09917 1/20 0.33
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30
PIM1 P11309 1/20 0.30
PIM2 Q9P1W9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL780723 0.98 LIMK1 (0.37) KDM4EATML3MBTL1LIMK1TSPO
SCHEMBL780663 0.97 LIMK1 (0.35) KDM4EATML3MBTL1LIMK1TSPO
SCHEMBL780538 0.94 LIMK1 (0.36) LIMK1PIM3ALOX5TNKSTNKS2
SCHEMBL10165696 0.94 L3MBTL1 (0.43) KDM4EATML3MBTL1LIMK1TSPO
SCHEMBL780827 0.94 KDM4E (0.35) KDM4EATML3MBTL1LIMK1TSPO
SCHEMBL780761 0.93 KDM4E (0.35) KDM4EATML3MBTL1LIMK1TSPO
SCHEMBL780682 0.92 KDM4E (0.36) KDM4EATML3MBTL1LIMK1TSPO
SCHEMBL781299 0.92 KDM4E (0.36) KDM4EATML3MBTL1LIMK1TSPO
SCHEMBL18347186 0.92 LIMK1 (0.35) LIMK1PIM3ALOX5TNKSTNKS2
SCHEMBL780535 0.92 LIMK1 (0.35) KDM4EATML3MBTL1LIMK1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 KDM4E 3917/4885ATM 2271/4885L3MBTL1 947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.