SCHEMBL10165767

SCHEMBL10165767

c1ccc(-c2cc(-c3ccccc3)c3oc4c(-c5ccc6c(c5)c5ccccc5n6-c5ccccc5)cc(-c5ccccc5)cc4c3c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ATM Q13315 1/20 0.47
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 2/20 0.39
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.39
BRCA1 P38398 1/20 0.39
IL1R1 P14778 1/20 0.35
TSPO P30536 1/20 0.35
HDAC4 P56524 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
PTGER4 P35408 1/20 0.34
PLA2G2A P14555 1/20 0.32
PLA2G4A P47712 1/20 0.32
PRKDC P78527 2/20 0.31
EDNRB P24530 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL781515 0.93 KDM4E (0.40) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL781240 0.93 KDM4E (0.40) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL781580 0.91 KDM4E (0.38) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL781141 0.91 ATM (0.38) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL780904 0.90 KDM4E (0.36) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL10165771 0.90 L3MBTL1 (0.43) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL781213 0.90 KDM4E (0.35) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL781093 0.90 KDM4E (0.35) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL15790660 0.90 KDM4E (0.37) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL781381 0.90 KDM4E (0.37) L3MBTL1KDM4EATMKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element NUTF2, BRI3BP, CLINT1 L3MBTL1 1016/4885KDM4E 2172/4885ATM 2465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.