SCHEMBL10165768

SCHEMBL10165768

c1ccc(-n2c3ccccc3c3ccc(-c4cccc5c4oc4ccccc45)cc32)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.54
ATM Q13315 2/20 0.46
KDM4E B2RXH2 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PRKDC P78527 7/20 0.46
GGPS1 O95749 1/20 0.41
PTGES2 Q9H7Z7 1/20 0.39
ALDH1A1 P00352 4/20 0.37
PPARG P37231 2/20 0.37
RXFP1 Q9HBX9 2/20 0.37
NR2E3 Q9Y5X4 2/20 0.37
NCOR2 Q9Y618 2/20 0.37
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
POLB P06746 2/20 0.36
MEN1 O00255 1/20 0.36
TSHR P16473 1/20 0.36
BRCA1 P38398 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10165774 0.97 ALOX5 (0.57) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL18706121 0.95 ALOX5 (0.50) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL26060125 0.95 ALOX5 (0.50) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL17285329 0.95 ALOX5 (0.49) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL16904459 0.95 ALOX5 (0.52) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL19238730 0.95 ALOX5 (0.49) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL26788640 0.94 ALOX5 (0.49) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL17660889 0.94 ALOX5 (0.49) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL24810447 0.94 ALOX5 (0.48) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL18962966 0.94 ALOX5 (0.48) ALOX5ATMKDM4EL3MBTL1PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210004-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-06-29 US disclosed
US-20230210004-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-06-29 US disclosed
US-11588117-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2023-02-21 US disclosed
EP-3806176-A1 ELECTRONIC DEVICE Merck Patent GmbH (DE) 2021-04-14 EP disclosed
EP-2915199-B1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2021-03-31 EP disclosed
EP-3647393-A1 MATERIALS FOR ELECTRONIC DEVICES Merck Patent GmbH (DE) 2020-05-06 EP disclosed
US-10622570-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2020-04-14 US disclosed
US-20190088883-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2019-03-21 US disclosed
EP-3439058-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2019-02-06 EP disclosed
US-9831441-B2 Electronic device MERCK PATENT GMBH (DE) 2017-11-28 US disclosed
US-20160181548-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-06-23 US disclosed
US-20160181548-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-06-23 US disclosed
US-20150280133-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2015-10-01 US disclosed
US-20150280133-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2015-10-01 US disclosed
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
WO-2015014434-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-02-05 WO disclosed
WO-2014067614-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2014-05-08 WO disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10622570-B2 Organic electroluminescent element NR2E3, ESR1, NCOR2 ALOX5 670/4885ATM 4041/4885KDM4E 406/4885
US-20150280133-A1 ELECTRONIC DEVICE ECE2, EPHX1, ETV6 ALOX5 1888/4885ATM 4134/4885KDM4E 951/4885
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element NUTF2, BRI3BP, CLINT1 ALOX5 1931/4885ATM 2465/4885KDM4E 2172/4885
US-20160181548-A1 MATERIALS FOR ELECTRONIC DEVICES EPHB3, EPHA3, EPHB4 ALOX5 3227/4885ATM 4021/4885KDM4E 1241/4885
US-20230210004-A1 MATERIALS FOR ELECTRONIC DEVICES EPHB3, EPHA3, EPHB4 ALOX5 3227/4885ATM 4021/4885KDM4E 1241/4885
US-11588117-B2 Materials for electronic devices EPHB3, EPHA3, EPHB4 ALOX5 3227/4885ATM 4021/4885KDM4E 1241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.