Sugi Predict

Sugi Predict / Compounds / SCHEMBL10165774

SCHEMBL10165774

SCHEMBL10165774

c1ccc(-n2c3cc(-c4cccc5c4oc4ccccc45)ccc3c3ccc(-c4cccc5c4oc4ccccc45)cc32)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.57
▸ PRKDC P78527 7/20 0.47
▸ GGPS1 O95749 1/20 0.43
▸ ATM Q13315 2/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ PTGES2 Q9H7Z7 1/20 0.40
▸ ALDH1A1 P00352 3/20 0.39
▸ PPARG P37231 2/20 0.39
▸ RXFP1 Q9HBX9 2/20 0.39
▸ NR2E3 Q9Y5X4 2/20 0.39
▸ NCOR2 Q9Y618 2/20 0.39
▸ PRMT5 O14744 1/20 0.37
▸ WDR77 Q9BQA1 1/20 0.37
▸ PIK3CD O00329 2/20 0.36
▸ PIK3CB P42338 2/20 0.36
▸ AHR P35869 1/20 0.34
▸ LMNA P02545 2/20 0.34
▸ POLB P06746 1/20 0.34
▸ PIK3CA P42336 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10165768 0.97 ALOX5 (0.54) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL10165776 0.96 ALOX5 (0.53) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL21365522 0.95 ALOX5 (0.54) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL18706121 0.93 ALOX5 (0.50) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL31001617 0.93 ALOX5 (0.50) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL26060125 0.93 ALOX5 (0.50) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL16904459 0.92 ALOX5 (0.52) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL19238730 0.92 ALOX5 (0.49) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL17285329 0.92 ALOX5 (0.49) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL19213238 0.92 ALOX5 (0.54) ALOX5PRKDCGGPS1ATMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 — — US disclosed
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 — — US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 — — US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element NUTF2, BRI3BP, CLINT1 ALOX5 1931/4885PRKDC 2968/4885GGPS1 2686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.