Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.58 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.58 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.58 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276945 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLAGRM8GRM6 | |
| SCHEMBL18557284 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLAGRM8GRM6 | |
| SCHEMBL30760990 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLAGRM8GRM6 | |
| SCHEMBL27599412 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLAGRM8GRM6 | |
| SCHEMBL1276949 | 1.00 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLAGRM8GRM6 | |
| SCHEMBL28489878 | 0.97 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGRM8GRM6 | |
| SCHEMBL29517538 | 0.97 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGRM8GRM6 | |
| SCHEMBL29511419 | 0.97 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGRM8GRM6 | |
| SCHEMBL30798162 | 0.97 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGRM8GRM6 | |
| SCHEMBL29682236 | 0.97 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670268-A | Fusion proteins comprising E2 ubiquitin or ubiquitin-like conjugation domains and targeting domains for specific protein degradation | 免疫医疗有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-114702581-A | Universal carbohydrate compositions and methods for enhancing antibody efficacy | 台湾地区“中央研究院” | 2022-07-05 | — | — | CN | disclosed |
| CN-114437173-A | Novel peptides and uses thereof | 森纳生物科学公司 | 2022-05-06 | — | — | CN | disclosed |
| US-20210177857-A1 | THERAPEUTIC NANOPARTICLES COMPRISING A THERAPEUTIC AGENT AND METHODS OF MAKING AND USING THE SAME | PFIZER INC. (US) | 2021-06-17 | — | — | US | disclosed |
| US-10952972-B2 | Therapeutic nanoparticles comprising a therapeutic agent and methods of making and using same | PFIZER INC. (US) | 2021-03-23 | — | — | US | disclosed |
| EP-3511019-B1 | THERAPEUTIC NANOPARTICLES COMPRISING A THERAPEUTIC AGENT AND METHODS OF MAKING AND USING SAME | PFIZER (US) | 2020-10-14 | — | — | EP | disclosed |
| EP-2774608-B1 | Drug loaded polymeric nanoparticles and methods of making and using same | PFIZER (US) | 2019-11-20 | — | — | EP | disclosed |
| US-20190269617-A1 | Methods of Controlling Morphology of Polymeric Nanoparticles | PFIZER INC. (US) | 2019-09-05 | — | — | US | disclosed |
| EP-3511019-A1 | THERAPEUTIC NANOPARTICLES COMPRISING A THERAPEUTIC AGENT AND METHODS OF MAKING AND USING SAME | Pfizer Inc (US) | 2019-07-17 | — | — | EP | disclosed |
| EP-3116547-B1 | THERAPEUTIC NANOPARTICLES COMPRISING A THERAPEUTIC AGENT AND METHODS OF MAKING AND USING SAME | PFIZER (US) | 2019-06-05 | — | — | EP | disclosed |
| US-8420123-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | BIND BIOSCIENCES, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-20120288541-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | PFIZER INC. | 2012-11-15 | — | — | US | disclosed |
| US-8293276-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | BIND BIOSCIENCES, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-8236330-B2 | Cancer cell targeting using nanoparticles | BIND BIOSCIENCES, INC. (US) | 2012-08-07 | — | — | US | disclosed |
| US-8206747-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | BIND BIOSCIENCES, INC. (US) | 2012-06-26 | — | — | US | disclosed |
| EP-2436376-A1 | Cancer cell targeting using nanoparticles | Bind Biosciences, Inc. (US) | 2012-04-04 | — | — | EP | disclosed |
| US-20110274759-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | PFIZER INC. | 2011-11-10 | — | — | US | disclosed |
| US-20110224288-A1 | Cancer Cell Targeting Using Nanoparticles | PFIZER INC. | 2011-09-15 | — | — | US | disclosed |
| US-20100068285-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | PFIZER INC. | 2010-03-18 | — | — | US | disclosed |
| WO-2008121949-A1 | CANCER CELL TARGETING USING NANOPARTICLES | BIND BIOSCIENCES, INC. (US) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110274759-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | LDHA, LDHB, LPXN | FOLH1 177/4885NAALAD2 2442/4885RIMKLA 1489/4885 |
| US-20110224288-A1 | Cancer Cell Targeting Using Nanoparticles | CD47, EPCAM, CD44 | FOLH1 279/4885NAALAD2 1525/4885RIMKLA 3697/4885 |
| US-20100068285-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | CD47, LPXN, CD44 | FOLH1 173/4885NAALAD2 2614/4885RIMKLA 1707/4885 |
| US-20190269617-A1 | Methods of Controlling Morphology of Polymeric Nanoparticles | CLTB, NCL, ACTB | FOLH1 828/4885NAALAD2 3320/4885RIMKLA 1643/4885 |
| US-10952972-B2 | Therapeutic nanoparticles comprising a therapeutic agent and methods of making and using same | CTSA, GAA, EEA1 | FOLH1 135/4885NAALAD2 1736/4885RIMKLA 3209/4885 |
| US-20120288541-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | CD47, LPXN, CD44 | FOLH1 173/4885NAALAD2 2614/4885RIMKLA 1707/4885 |
| US-20210177857-A1 | THERAPEUTIC NANOPARTICLES COMPRISING A THERAPEUTIC AGENT AND METHODS OF MAKING AND USING THE SAME | TP53, HNRNPH3, VHL | FOLH1 336/4885NAALAD2 1694/4885RIMKLA 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.