⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786076 | 0.83 | — | — | |
| SCHEMBL11145930 | 0.81 | — | — | |
| SCHEMBL14084915 | 0.77 | — | — | |
| SCHEMBL2337430 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL8511721 | 0.77 | — | — | |
| SCHEMBL28350080 | 0.75 | — | — | |
| Bromide SCHEMBL7075724 | 0.75 | CHRM2 (0.32) | — | |
| SCHEMBL18414048 | 0.73 | — | — | |
| SCHEMBL13316206 | 0.73 | CHRNB2 (0.39) | — | |
| SCHEMBL15362873 | 0.73 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1067 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980319-B2 | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans | MALLINCKRODT LLC (US) | 2015-03-17 | — | — | US | claimed |
| US-20140086987-A1 | Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans | MALLINCKRODT LLC (US) | 2014-03-27 | — | — | US | claimed |
| US-20140044786-A1 | ONCE-WEEKLY ORAL ADMINISTRATION OF ARIPIPRAZOLE | ZYSIS LIMITED (GB) | 2014-02-13 | — | — | US | claimed |
| US-8597681-B2 | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans | MALLINCKRODT LLC (US) | 2013-12-03 | — | — | US | claimed |
| WO-2008027442-A2 | ABUSE DETERRENT ORAL PHARMACEUTICAL FORMULATIONS OF OPIOID AGONISTS AND METHOD OF USE | THERAQUEST BIOSCIENCES, LLC (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008021394-A2 | PHARMACEUTICAL FORMULATIONS OF CANNABINOIDS AND METHOD OF USE | THERAQUEST BIOSCIENCES, LLC (US) | 2008-02-21 | — | — | WO | claimed |
| WO-2006002031-A1 | SUSTAINED RELEASE DOSAGE FORMS | ANDRX CORPORATION (US) | 2006-01-05 | — | — | WO | claimed |
| US-20050276849-A1 | Sustained release dosage forms | ANDRX CORPORATION | 2005-12-15 | — | — | US | claimed |
| WO-2004098562-A2 | CONTROLLED RELEASE SOLID DOSAGE NIFEDIPINE FORMULATIONS | NOVEON IP HOLDINGS CORP. (US) | 2004-11-18 | — | — | WO | claimed |
| US-20040219210-A1 | Controlled release solid dosage nifedipine formulations | LUBRIZOL ADVANCED MATERIALS, INC. | 2004-11-04 | — | — | US | claimed |
| US-5840329-A | GROUPS OF PARTICLES HAVING DISTINCT PATTERN OF DRUG RELEASE BASED ON COMBINATION OF CONTROLLED RELEASE LAYERS, SWELLING AGENTS AND COATINGS; CONTROLLED RELEASE LAYER OF SLIGHTLY CROSSLINKED POLYACRYLIC ACID AND WATER SOLUBLE POLYMER | BIOADVANCES LLC (US) | 1998-11-24 | — | — | US | claimed |
| WO-1998051287-A1 | PULSATILE DRUG DELIVERY SYSTEM | BAI JANE PEI FAN (US) | 1998-11-19 | — | — | WO | claimed |
| US-4116241-A | FOR CONTROLLED ORAL ADMINISTRATION OF DRUG | ALZA CORPORATION (US) | 1978-09-26 | — | — | US | claimed |
| US-20240156811-A1 | COMBINATIONS COMPRISING BREXPIPRAZOLE OR A SALT THEREOF AND A SECOND DRUG FOR USE IN THE TREATMENT OF A CNS DISORDER | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-05-16 | — | — | US | disclosed |
| CN-112469402-B | Orally administrable and sustained release pharmaceutical dosage forms | 拜耳公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-108836948-B | Product capable of realizing controllable release of nutrients by coating technology | 宁波西敦医药包衣科技有限公司 | 2024-04-12 | — | — | CN | disclosed |
| US-4077407-A | POLYSACCHARIDES | ALZA CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
| US-4058122-A | Osmotic system with laminated wall formed of different materials | ALZA CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |
| US-4014334-A | Laminated osmotic system for dispensing beneficial agent | ALZA CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
| US-4008719-A | Osmotic system having laminar arrangement for programming delivery of active agent | ALZA CORPORATION (US) | 1977-02-22 | — | — | US | disclosed |