Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 3/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL356263 | 0.91 | CARM1 (0.33) | DHODHCARM1MAPTGPBAR1TRPA1 | |
| SCHEMBL10167610 | 0.91 | MAPT (0.34) | DHODHCARM1MALT1MAPTRBP4 | |
| SCHEMBL10167629 | 0.88 | DHODH (0.42) | DHODHMALT1MAPTRBP4 | |
| SCHEMBL10167606 | 0.84 | DHODH (0.39) | DHODHCARM1MALT1MAPTRBP4 | |
| SCHEMBL357902 | 0.83 | CARM1 (0.32) | CARM1TRPA1TRPV1ALPL | |
| SCHEMBL10167621 | 0.80 | DHODH (0.36) | DHODHMAPT | |
| SCHEMBL10167587 | 0.75 | KLKB1 (0.38) | CARM1MALT1MAPTTRPV1 | |
| SCHEMBL10167593 | 0.75 | MAPT (0.37) | DHODHCARM1MALT1MAPTTRPV1 | |
| SCHEMBL10167663 | 0.74 | KLKB1 (0.36) | DHODHCARM1MALT1MAPTTRPV1 | |
| SCHEMBL10167682 | 0.73 | KLKB1 (0.36) | DHODHCARM1MALT1MAPTTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119568-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest II | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119568-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest II | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BASF SE (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BASF SE (DE) | 2010-01-14 | — | — | US | disclosed |
| WO-2008090048-A2 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2008-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BPNT1, BCAT1, TGFBR1 | DHODH 3334/4885CARM1 514/4885MALT1 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.