⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276925 | 0.90 | — | — | |
| SCHEMBL10503416 | 0.87 | TSHR (0.50) | — | |
| SCHEMBL10503065 | 0.87 | TSHR (0.50) | — | |
| SCHEMBL10502952 | 0.87 | TSHR (0.50) | — | |
| SCHEMBL277022 | 0.87 | — | — | |
| SCHEMBL103685 | 0.87 | TSHR (0.50) | — | |
| SCHEMBL10502676 | 0.87 | TSHR (0.50) | — | |
| SCHEMBL104136 | 0.87 | TSHR (0.50) | — | |
| SCHEMBL10503195 | 0.87 | TSHR (0.50) | — | |
| SCHEMBL10502961 | 0.87 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 978 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024127026-A1 | MEMBRANE FILTRATION-ASSISTED SOLUTION PHASE OLIGONUCLEOTIDE SYNTHESIS | Exactmer Limited (GB) | 2024-06-20 | — | — | WO | claimed |
| CN-110099682-A | Coupled connector, cell binding molecule-drug conjugate containing same, and preparation and application thereof | 杭州多禧生物科技有限公司 | 2019-08-06 | — | — | CN | claimed |
| EP-2567964-B1 | Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection | AGILENT TECHNOLOGIES INC (US) | 2015-02-11 | — | — | EP | claimed |
| US-8530662-B2 | Pyridyltetrahydropyridines and pyridylpiperidines, and method of manufacturing them | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2013-09-10 | — | — | US | claimed |
| EP-2567964-A2 | Monomer Compositions for the Synthesis of RNA, Methods of Synthesis, and Methods of Deprotection | Agilent Technologies, Inc. (US) | 2013-03-13 | — | — | EP | claimed |
| US-8084613-B2 | Tetrazoyloxime derivative and plant disease control agent | NIPPON SODA CO., LTD. (JP) | 2011-12-27 | — | — | US | claimed |
| US-7759471-B2 | nucleotide monomer used to make protected RNA that has similar stability to the DNA molecule | AGILENT TECHNOLOGIES, INC. (US) | 2010-07-20 | — | — | US | claimed |
| EP-1180991-B1 | GAMBOGIC ACID DERIVATIVES AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS | CYTOVIA INC (US) | 2010-05-19 | — | — | EP | claimed |
| EP-2001896-A2 | MONOMER COMPOSITIONS FOR THE SYNTHESIS OF RNA, METHODS OF SYNTHESIS, AND METHODS OF DEPROTECTION | Agilent Technologies, Inc. (US) | 2008-12-17 | — | — | EP | claimed |
| WO-2007112263-A2 | MONOMER COMPOSITIONS FOR THE SYNTHESIS OF RNA, METHODS OF SYNTHESIS, AND METHODS OF DEPROTECTION | AGILENT TECHNOLOGIES, INC. (US) | 2007-10-04 | — | — | WO | claimed |
| EP-0362634-A2 | Basic dihydropyridines, process for their preparation and their use as intermediates | BAYER AG (DE) | 1990-04-11 | — | — | EP | claimed |
| US-4845106-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-07-04 | — | — | US | claimed |
| US-4742060-A | 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1988-05-03 | — | — | US | claimed |
| EP-0217804-A1 | ANALOGS OF SUBSTANCES P. | ENICHEM SPA (IT) | 1987-04-15 | — | — | EP | claimed |
| US-4638046-A | Retro-inverso C-terminal hexapeptide analogues of substance P | ENI-ENTE NAZIONALE IDROCARBURI (IT) | 1987-01-20 | — | — | US | claimed |
| WO-1986003495-A2 | DERIVATIVES OF SUBSTANCES P AND OF FRAGMENTS THEREOF | ENICHEM S.P.A. (IT) | 1986-06-19 | — | — | WO | claimed |
| EP-0082568-B1 | RETRO-INVERSO ANALOGUES OF C-TERMINAL PENTA AND HEXAPEPTIDES OF SUBSTANCE P. | ANIC S.p.A. (IT) | 1984-11-21 | — | — | EP | claimed |
| US-4439360-A | Retro-inverso analogues of C-terminal penta and hexapeptides of Substance P | ANIC S.P.A. (IT) | 1984-03-27 | — | — | US | claimed |
| US-4405782-A | Process for the preparation of solutions of 7-aminocephalosporanic acids | GEMA, S.A. (ES) | 1983-09-20 | — | — | US | claimed |
| EP-0082568-A2 | Retro-inverso analogues of C-terminal penta and hexapeptides of substance P. | ANIC S.p.A. (IT) | 1983-06-29 | — | — | EP | claimed |