Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.67 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.67 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18745789 | 1.00 | MAPT (0.67) | MAPTCYP3A4ALDH1A1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL4442125 | 0.97 | CYP3A4 (0.64) | MAPTCYP3A4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL18745800 | 0.86 | CYP3A4 (0.53) | MAPTCYP3A4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL18745703 | 0.86 | CYP3A4 (0.58) | MAPTCYP3A4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10000032 | 0.84 | MAPT (0.92) | MAPTCYP3A4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL135626 | 0.84 | MAPT (0.92) | MAPTCYP3A4ALDH1A1SMN1; SMN2MEN1 | |
| Benzidine SCHEMBL28084578 | 0.83 | CYP3A4 (0.62) | MAPTCYP3A4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL18448794 | 0.83 | ALDH1A1 (0.52) | MAPTCYP3A4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9098509 | 0.82 | NPC1 (0.80) | MAPTCYP3A4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9098395 | 0.82 | NPC1 (0.80) | MAPTCYP3A4ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117577828-B | Long-cycle lithium battery positive electrode material and preparation method thereof | 智泰新能源(东台)有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117577828-A | Long-cycle lithium battery positive electrode material and preparation method thereof | 智泰新能源(东台)有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-116970179-A | Preparation and application of heteropoly acid-triarylamine double-active-center metal organic framework with photocatalysis alpha-amino C-H functionalization performance | 大连理工大学 | 2023-10-31 | — | — | CN | claimed |
| CN-116903857-A | Pyridine ion porous organic polymer, preparation method and application thereof | 浙江工业大学 | 2023-10-20 | — | — | CN | claimed |
| CN-116496304-A | Cadmium-based metal organic complex with thermochromic performance, and preparation method and application thereof | 常州大学 | 2023-07-28 | — | — | CN | claimed |
| CN-114409919-B | Super-tetrahedral cluster-based coordination polymer material and preparation method and application thereof | 平顶山学院 | 2023-02-07 | — | — | CN | claimed |
| CN-114409919-A | Super-tetrahedral cluster-based coordination polymer material and preparation method and application thereof | 平顶山学院 | 2022-04-29 | — | — | CN | claimed |
| EP-2050749-B1 | PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2017-11-22 | — | — | EP | claimed |
| US-20100069629-A1 | PYRIMIDINE DERIVATIVES AS PI3K INHIBITOR AND USE THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-03-18 | — | — | US | claimed |
| EP-2050749-A1 | PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-04-22 | — | — | EP | claimed |
| US-20080167348-A1 | NOVEL SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-07-10 | — | — | US | claimed |
| US-4600678-A | CHROMOGENS, PHOTOINITIATORS, FREE RADICAL ADDITION POLYMERIZABLE MATERIAL | THE MEAD CORPORATION (US) | 1986-07-15 | — | — | US | claimed |
| US-4377585-A | Use of 4-[4(or 3)-aminophenyl]pyridines as cardiotonic agents | STERLING DRUG INC. (US) | 1983-03-22 | — | — | US | claimed |
| US-3994903-A | Preparation of 4-(3-nitrophenyl)pyridine | STERLING DRUG INC. (US) | 1976-11-30 | — | — | US | claimed |
| US-3985376-A | Dye precursors for pressure-sensitive recording material | BASF AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | claimed |
| EP-4737448-A1 | SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF | Artivila (ShenZhen) Innovation Center, Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| US-12590071-B2 | Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2026-03-31 | — | — | US | disclosed |
| US-3985376-A | Dye precursors for pressure-sensitive recording material | BASF AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |
| US-3985376-A | Dye precursors for pressure-sensitive recording material | BASF AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |
| US-3943125-A | Substituted tetraamino heterocyclic compounds, useful in the preparation of substituted polybenzimidazoles and poly-imidazopyrrolones | HORIZONS INCORPORATED, A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069629-A1 | PYRIMIDINE DERIVATIVES AS PI3K INHIBITOR AND USE THEREOF | PIK3CA, AKT3, AKT1 | MAPT 4385/4885CYP3A4 3027/4885ALDH1A1 2102/4885 |
| US-12590071-B2 | Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof | ABL1, TH, CYP3A43 | MAPT 3633/4885CYP3A4 27/4885ALDH1A1 1008/4885 |
| US-20080167348-A1 | NOVEL SULFONAMIDE DERIVATIVES | CMA1, ARSA, TPSAB1 | MAPT 4572/4885CYP3A4 1209/4885ALDH1A1 1277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.