SCHEMBL1016798

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3839129	0.83	MAPK14 (0.47)	HPGDSPDK2MAPK14LMNAHPGD
	SCHEMBL18446204	0.82	PDK2 (0.67)	HPGDSESR2PDK2MAPTLMNA
	SCHEMBL1778530	0.80	MAPK14 (0.67)	HPGDSMAPTMAPK14MEN1KMT2A
	SCHEMBL10095072	0.80	HPGDS (0.54)	HPGDSSLC34A1ESR2PDK2NR1H2
	SCHEMBL1779430	0.79	PDK2 (0.66)	HPGDSESR2PDK2NR1H2MAPT
	SCHEMBL16836285	0.79	SLC34A1 (0.50)	HPGDSSLC34A1ESR2PDK2NR1H2
	SCHEMBL10095073	0.79	GPR119 (0.53)	HPGDSSLC34A1ESR2PDK2NR1H2
	SCHEMBL20792752	0.78	PDK2 (0.69)	HPGDSSLC34A1ESR2PDK2MAPT
	SCHEMBL16836123	0.78	NR1H2 (0.58)	HPGDSSLC34A1ESR2PDK2NR1H2
	SCHEMBL10095071	0.77	HPGDS (0.53)	HPGDSSLC34A1ESR2PDK2NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.