SCHEMBL10168053

SCHEMBL10168053

CCO[C@@H]1C[C@H](O)C(CO)O1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 1/20 0.37
LGALS3 P17931 1/20 0.37
LGALS4 P56470 1/20 0.37
OGA O60502 4/20 0.37
STAT3 P40763 1/20 0.35
PDE4D Q08499 2/20 0.34
TK2 O00142 1/20 0.33
TK1 P04183 1/20 0.33
SLC5A2 P31639 1/20 0.32
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14525303 1.00 LGALS8 (0.37) LGALS8LGALS3LGALS4OGASTAT3
SCHEMBL24473712 0.89 LGALS3 (0.41) LGALS8LGALS3LGALS4STAT3PTPN1
SCHEMBL24491012 0.89 LGALS3 (0.41) LGALS8LGALS3LGALS4STAT3PTPN1
SCHEMBL8129184 0.83 OGA (0.31) OGASTAT3
SCHEMBL8129180 0.83 OGA (0.31) OGASTAT3
SCHEMBL3392883 0.81 LGALS8 (0.47) LGALS8LGALS3LGALS4OGA
SCHEMBL1842874 0.81 LGALS8 (0.47) LGALS8LGALS3LGALS4OGA
SCHEMBL14373147 0.81 STAT3 (0.35) STAT3
SCHEMBL14199486 0.80 OGA (0.37) LGALS8LGALS3LGALS4OGASTAT3
SCHEMBL18533110 0.80 OGA (0.37) LGALS8LGALS3LGALS4OGASTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1540013-B1 EVOLVING NEW MOLECULAR FUNCTION HARVARD COLLEGE (US) 2015-07-08 EP disclosed
US-8206914-B2 Evolving new molecular function PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2012-06-26 US disclosed
US-7998904-B2 Libraries of oligonucleotides created by genetic engineering PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2011-08-16 US disclosed
US-20110190141-A1 Evolving New Molecular Function PRESIDENT AND FELLOWS OF HAVARD COLLEGE (US) 2011-08-04 US disclosed
US-7771935-B2 Evolving new molecular function PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2010-08-10 US disclosed
US-7557068-B2 Evolving new molecular function PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2009-07-07 US disclosed
US-7491494-B2 Evolving new molecular function PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2009-02-17 US disclosed
US-7442160-B2 Evolving new molecular function PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2008-10-28 US disclosed