Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | VIPR2 | P41587 | 6/20 | 0.44 |
| ▸ | VIPR1 | P32241 | 4/20 | 0.44 |
| ▸ | HRAS | P01112 | 1/20 | 0.44 |
| ▸ | KRAS | P01116 | 1/20 | 0.44 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | TFPI | P10646 | 1/20 | 0.43 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 5/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10168607 | 0.87 | APLNR (0.51) | F2GLP1R | |
| SCHEMBL16299148 | 0.86 | F2 (0.52) | F2VIPR2VIPR1TFPIPTH1R | |
| SCHEMBL10169051 | 0.84 | TFPI (0.53) | F2KRASTFPIPTH1RGLP1R | |
| SCHEMBL30101001 | 0.83 | VIPR2 (0.47) | F2VIPR2VIPR1GLP1RTUBB4A | |
| SCHEMBL10168616 | 0.83 | APLNR (0.49) | F2GLP1RMC4R | |
| SCHEMBL17806529 | 0.83 | GLP1R (0.59) | GLP1R | |
| SCHEMBL29609528 | 0.82 | GLP1R (0.47) | F2GLP1RTUBB4ATUBBTUBA3C | |
| SCHEMBL22375041 | 0.82 | IL23R (0.50) | TFPI | |
| SCHEMBL10168278 | 0.82 | APLNR (0.49) | F2GLP1RMC4R | |
| SCHEMBL29904555 | 0.81 | NPY4R (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028888-A1 | APJ RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028888-A1 | APJ RECEPTOR COMPOUNDS | APLNR, AP1G1, AP2B1 | F2 4437/4885VIPR2 441/4885VIPR1 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.