Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL100167 | 0.93 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1MAPTTRPV1MEN1 | |
| SCHEMBL99813 | 0.87 | HCAR2 (0.44) | MAPTHDAC1HDAC2RAB9A | |
| SCHEMBL98208 | 0.85 | HCAR2 (0.41) | SMN1; SMN2ALDH1A1MAPTTRPV1MEN1 | |
| SCHEMBL661937 | 0.84 | CHRM3 (0.50) | — | |
| SCHEMBL100027 | 0.82 | GAA (0.39) | SMN1; SMN2ALDH1A1MEN1KMT2AHDAC1 | |
| SCHEMBL99669 | 0.82 | NPC1 (0.45) | SMN1; SMN2ALDH1A1MAPTMEN1CYP3A4 | |
| SCHEMBL102617 | 0.82 | HCAR2 (0.39) | SMN1; SMN2TRPV1MEN1KMT2AHDAC1 | |
| SCHEMBL99035 | 0.82 | HDAC1 (0.51) | SMN1; SMN2ALDH1A1MAPTTRPV1MEN1 | |
| SCHEMBL99375 | 0.82 | NPC1 (0.49) | SMN1; SMN2ALDH1A1MAPTTRPV1MEN1 | |
| SCHEMBL98250 | 0.82 | CHRM3 (0.56) | ALDH1A1MEN1TSHRKMT2ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | claimed |