Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99141 | 0.98 | NPC1 (0.48) | NPC1RAB9AHPGDPOLBMAPT | |
| SCHEMBL99071 | 0.96 | RAB9A (0.43) | NPC1RAB9AHDAC1HDAC2KMT2A | |
| SCHEMBL102179 | 0.92 | NPC1 (0.42) | NPC1RAB9APOLBMAPTKMT2A | |
| SCHEMBL102843 | 0.89 | HCAR2 (0.42) | NPC1RAB9APOLBMAPTHDAC1 | |
| SCHEMBL100167 | 0.89 | SMN1; SMN2 (0.43) | NPC1RAB9APOLBMAPTHDAC1 | |
| SCHEMBL99659 | 0.88 | POLB (0.40) | NPC1RAB9AHPGDPOLBMAPT | |
| SCHEMBL97653 | 0.88 | CHEK1 (0.42) | NPC1RAB9AHPGDPOLBMAPT | |
| SCHEMBL98208 | 0.87 | HCAR2 (0.41) | NPC1RAB9AHPGDPOLBMAPT | |
| SCHEMBL99703 | 0.86 | NPC1 (0.58) | NPC1RAB9AHPGDPOLBMAPT | |
| SCHEMBL663959 | 0.86 | CHRM3 (0.46) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | claimed |