Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL100167 | 0.94 | SMN1; SMN2 (0.43) | HCAR2HDAC1HDAC2MAPTRAB9A | |
| SCHEMBL99078 | 0.92 | HCAR2 (0.42) | HCAR2GHSRTOP2ATOP2BMAPT | |
| SCHEMBL102843 | 0.91 | HCAR2 (0.42) | HCAR2HDAC1HDAC2RORCMAPT | |
| SCHEMBL99712 | 0.90 | HDAC1 (0.40) | HCAR2HDAC1HTT | |
| SCHEMBL101458 | 0.89 | HCAR2 (0.45) | HCAR2MAPTHTTRAB9A | |
| SCHEMBL100524 | 0.89 | RORC (0.43) | HCAR2HDAC1HDAC2RORCMAPT | |
| SCHEMBL101812 | 0.89 | PTGDR2 (0.42) | HCAR2HDAC1HDAC2RORCMAPT | |
| SCHEMBL99071 | 0.88 | RAB9A (0.43) | HCAR2HDAC1HDAC2RAB9A | |
| SCHEMBL101243 | 0.87 | LMNA (0.41) | HCAR2MAPTHTTRAB9A | |
| SCHEMBL102082 | 0.87 | RAB9A (0.44) | HCAR2RORCRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | claimed |