Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20696421 | 0.85 | LPAR3 (0.44) | LPAR3LPAR2LPAR1LPAR5SMPD1 | |
| SCHEMBL20977065 | 0.78 | ALDH1A1 (0.38) | — | |
| SCHEMBL19201602 | 0.76 | BTN3A1 (0.31) | LPAR3LPAR2LPAR1 | |
| SCHEMBL10071830 | 0.76 | SMPD1 (0.38) | LPAR3LPAR2LPAR1SMPD1S1PR4 | |
| SCHEMBL15445131 | 0.75 | — | — | |
| SCHEMBL23263121 | 0.75 | LPAR3 (0.40) | LPAR3LPAR2LPAR1LPAR5SMPD1 | |
| Propyl Phosphate SCHEMBL28303359 | 0.75 | LPAR3 (0.65) | LPAR3LPAR2LPAR1LPAR5 | |
| Propyl Phosphate SCHEMBL57642 | 0.75 | — | — | |
| SCHEMBL12146535 | 0.74 | TSHR (0.30) | — | |
| Propyl Phosphate SCHEMBL17255183 | 0.73 | LPAR3 (0.58) | LPAR3LPAR2LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046757-A1 | COVALENT MODIFICATION OF METAL SURFACES | INTEZYNE TECHNOLOGIES (US) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046757-A1 | COVALENT MODIFICATION OF METAL SURFACES | ITGAL, ITGA1, ITGA5 | LPAR3 4317/4885LPAR2 4339/4885LPAR1 4255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.