Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | STS | P08842 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765877 | 0.91 | CASP2 (0.48) | CASP2FAAHEPHX2SLC6A5NAAA | |
| SCHEMBL12334401 | 0.91 | CASP2 (0.48) | CASP2FAAHEPHX2SLC6A5NAAA | |
| SCHEMBL765226 | 0.87 | FAAH (0.48) | CASP2FAAHEPHX2SLC6A5NAAA | |
| SCHEMBL10171436 | 0.87 | FAAH (0.48) | CASP2FAAHEPHX2SLC6A5NAAA | |
| SCHEMBL16327170 | 0.87 | FAAH (0.48) | CASP2FAAHEPHX2SLC6A5NAAA | |
| SCHEMBL10170351 | 0.83 | FAAH (0.47) | CASP2FAAHEPHX2SLC6A5NAAA | |
| SCHEMBL10170582 | 0.83 | FAAH (0.47) | CASP2FAAHEPHX2SLC6A5NAAA | |
| SCHEMBL17740092 | 0.83 | CASP2 (0.62) | CASP2FAAHEPHX2SLC6A5NAAA | |
| SCHEMBL10171347 | 0.83 | CASP2 (0.62) | CASP2FAAHEPHX2SLC6A5NAAA | |
| SCHEMBL10171418 | 0.83 | CASP2 (0.62) | CASP2FAAHEPHX2SLC6A5NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708755-B1 | TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES | NOVO NORDISK HEALTHCARE AG (CH) | 2012-03-21 | — | — | EP | disclosed |