SCHEMBL101704

SCHEMBL101704

CONCc1c[nH]c(=S)[nH]c1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPT P10636 2/20 0.40
KDM3B Q7LBC6 1/20 0.39
ERAP1 Q9NZ08 1/20 0.35
RXFP1 Q9HBX9 2/20 0.35
PPARG P37231 1/20 0.35
NCOA2 Q15596 1/20 0.35
NCOA1 Q15788 1/20 0.35
NCOA3 Q9Y6Q9 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.33
UBE2N P61088 1/20 0.33
ALDH1A1 P00352 2/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
KDM4E B2RXH2 1/20 0.31
APAF1 O14727 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3453954 0.89 KMT2A (0.42) KMT2ATDP1MAPT
Thiouracil SCHEMBL27583653 0.81 TP53 (0.47) KMT2ATDP1
SCHEMBL153562 0.81 KMT2A (0.50) KMT2ATDP1KDM3BERAP1UBE2N
SCHEMBL29007135 0.77 KMT2A (0.54) KMT2ATDP1MAPTKDM3BERAP1
SCHEMBL3540299 0.76 KMT2A (0.60) KMT2ATDP1KDM3BRXFP1MEN1
SCHEMBL2384930 0.73 KMT2A (0.50) KMT2ATDP1MAPTKDM3BERAP1
SCHEMBL9108064 0.73 KMT2A (0.57) KMT2ATDP1MAPTKDM3BRXFP1
SCHEMBL10918304 0.72 ERAP1 (0.60) KMT2ATDP1ERAP1L3MBTL1MEN1
SCHEMBL1691795 0.72 KMT2A (0.55) KMT2ATDP1KDM3BRXFP1MEN1
SCHEMBL104627 0.71 KMT2A (0.48) KMT2ATDP1KDM3BRXFP1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 19616 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577554-B2 Methods for purification of messenger RNA TRANSLATE BIO, INC. (US) 2026-03-17 US claimed
US-12569572-B2 Messenger RNA therapy for the treatment of Friedreich's ataxia TRANSLATE BIO, INC. (US) 2026-03-10 US claimed
US-12552858-B2 Methods and compositions for delivering mRNA coded antibodies TRANSLATE BIO, INC. (US) 2026-02-17 US claimed
EP-4659246-A1 ELECTROCHEMICAL SYNTHESIS WITH REDOX STABLE NUCLEOTIDES Atlas Data Storage, Inc. (US) 2025-12-10 EP claimed
US-20250368986-A1 ELECTROCHEMICAL SYNTHESIS WITH REDOX STABLE NUCLEOTIDES ATLAS DATA STORAGE INC (US) 2025-12-04 US claimed
US-20250257360-A1 OLIGONUCLEOTIDE INTERFERENCE TREATMENTS OF PROSTATE CANCER UNIV OKLAHOMA (US) 2025-08-14 US claimed
WO-2025137576-A1 MULTIPLE SPECIFIC ANTIBODIES TARGETING CD19, CD20, AND/OR CD47 NUTCRACKER THERAPEUTICS, INC. (US) 2025-06-26 WO claimed
US-20250066799-A1 UNNATURAL BASE PAIR COMPOSITIONS AND METHODS OF USE THE SCRIPPS RESEARCH INSTITUTE 2025-02-27 US claimed
EP-4504945-A2 OLIGONUCLEOTIDE INTERFERENCE TREATMENTS OF PROSTATE CANCER The Board of Regents of the University of Oklahoma (US) 2025-02-12 EP claimed
US-12146139-B2 Oligonucleotide interference treatments of prostate cancer THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2024-11-19 US claimed
US-20090227489-A1 STAT3 Agonists and Antagonists and Therapeutic Uses Thereof JOHNS HOPKINS UNIVERSITY (US) 2009-09-10 US claimed
WO-2008083949-A2 RNA-CODED ANTIBODY CUREVAC GMBH (DE) 2008-07-17 WO claimed
EP-1308511-A1 Use of angiopoietin-like 1 and angiopoietin-like 2 nucleic acids and proteins for the treatment of blood-related disorders and defects in vasculature. Mermaid Pharmaceuticals GmbH (DE) 2003-05-07 EP claimed
EP-1295130-A2 NIMR COMPOSITIONS AND THEIR METHODS OF USE TRUSTEES OF TUFTS COLLEGE (US) 2003-03-26 EP claimed
JP-2002531470-A 2002-09-24 JP claimed
EP-1163374-A2 ARRAYS OF ORGANIC COMPOUNDS ATTACHED TO SURFACES Syntrix Biochip, Inc. (US) 2001-12-19 EP claimed
WO-2001070776-A2 NIMR COMPOSITIONS AND THEIR METHODS OF USE TRUSTEES OF TUFTS COLLEGE (US) 2001-09-27 WO claimed
WO-2000033084-A2 ARRAYS OF ORGANIC COMPOUNDS ATTACHED TO SURFACES SYNTRIX BIOCHIP, INC. (US) 2000-06-08 WO claimed
WO-1998042723-A9 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF NEUROPSYCHIATRIC DISORDERS 1999-03-04 WO claimed
US-5486603-A Oligonucleotide having enhanced binding affinity GILEAD SCIENCES, INC. (US) 1996-01-23 US claimed