Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.62 |
| ▸ | PPP3CB | P16298 | 1/20 | 0.62 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.53 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14403900 | 0.93 | CTSB (0.53) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL12514207 | 0.93 | CTSB (0.67) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL10170518 | 0.92 | CTSB (0.72) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL10137393 | 0.92 | CTSB (0.72) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL13763572 | 0.88 | CTSB (0.69) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL13707479 | 0.86 | CTSB (0.81) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL8300978 | 0.85 | CTSB (0.71) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL10170493 | 0.85 | CTSB (0.70) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL13707478 | 0.84 | CTSB (0.54) | CTSBPPP3CBABCC1ABCC2ABCG2 | |
| SCHEMBL13757651 | 0.83 | CTSB (0.69) | CTSBPPP3CBABCC1ABCC2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120269769-A1 | Hepatitis C Inhibitor Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-10-25 | — | — | US | disclosed |
| US-20120034187-A1 | Hepatitis C Inhibitor Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-09 | — | — | US | disclosed |
| US-8067438-B2 | Hepatitis C inhibitor compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-29 | — | — | US | disclosed |
| US-20110177030-A1 | Hepatitis C Inhibitor Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-21 | — | — | US | disclosed |
| US-7939667-B2 | Hepatitis C inhibitor compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-05-10 | — | — | US | disclosed |
| US-20070243166-A1 | Hepatitis C Inhibitor Compounds | LLINAS-BRUNET MONTSE | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120269769-A1 | Hepatitis C Inhibitor Compounds | HAVCR2, CTRL, CTRC | CTSB 103/4885PPP3CB 722/4885ABCC1 121/4885 |
| US-20070243166-A1 | Hepatitis C Inhibitor Compounds | HAVCR2, CTRL, CTRC | CTSB 103/4885PPP3CB 722/4885ABCC1 121/4885 |
| US-20120034187-A1 | Hepatitis C Inhibitor Compounds | HAVCR2, CTRL, CTRC | CTSB 103/4885PPP3CB 722/4885ABCC1 121/4885 |
| US-20110177030-A1 | Hepatitis C Inhibitor Compounds | HAVCR2, CTRL, CTRC | CTSB 103/4885PPP3CB 722/4885ABCC1 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.