Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19502509 | 0.92 | SHBG (0.41) | SHBGTSHR | |
| SCHEMBL10750 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL19732792 | 0.76 | — | — | |
| SCHEMBL2493309 | 0.73 | SHBG (0.50) | SHBGTSHRDPP4DPP7EPHX2 | |
| SCHEMBL7761566 | 0.73 | SHBG (0.44) | SHBGTSHRLMNACYP2C9 | |
| SCHEMBL14738797 | 0.73 | SHBG (0.39) | SHBGTSHR | |
| SCHEMBL24008443 | 0.72 | CHRM5 (0.36) | — | |
| SCHEMBL3112779 | 0.71 | SHBG (0.48) | SHBGTSHREPHX2 | |
| SCHEMBL21828198 | 0.71 | — | — | |
| SCHEMBL2700308 | 0.71 | TSHR (0.64) | SHBGTSHRLMNACYP2C9EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3353155-A1 | PYRIDYL OR PYRAZINYL COMPOUNDS CARRYING A METHYL-BOUND ALPHA-AMINO ACID AMIDE GROUP | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-08-01 | — | — | EP | disclosed |
| WO-2017050807-A1 | PYRIDYL OR PYRAZINYL COMPOUNDS CARRYING A METHYL-BOUND ALPHA-AMINO ACID AMIDE GROUP | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-03-30 | — | — | WO | disclosed |
| WO-2012022793-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-23 | — | — | WO | disclosed |