Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10170867 | 0.73 | SHBG (0.46) | SHBGTSHR | |
| SCHEMBL13177782 | 0.73 | SHBG (0.46) | SHBGTSHR | |
| SCHEMBL7761566 | 0.70 | SHBG (0.44) | SHBGTSHR | |
| SCHEMBL19502509 | 0.67 | SHBG (0.41) | SHBGTSHR | |
| SCHEMBL2493309 | 0.66 | SHBG (0.50) | SHBGTSHR | |
| SCHEMBL3112779 | 0.64 | SHBG (0.48) | SHBGTSHR | |
| SCHEMBL28182 | 0.63 | — | — | |
| SCHEMBL102859 | 0.63 | — | — | |
| SCHEMBL2700308 | 0.63 | TSHR (0.64) | SHBGTSHR | |
| SCHEMBL3389566 | 0.63 | TSHR (0.64) | SHBGTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130059821-A1 | BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS | BIOGEN MA INC. | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059821-A1 | BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS | S1PR1, S1PR2, S1PR3 | SHBG 4144/4885TSHR 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.