SCHEMBL1017104

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1017851	0.93	MEN1 (0.49)	ALDH1A1MEN1KMT2APKMKDM4E
	SCHEMBL1017273	0.89	HRH3 (0.42)	ALDH1A1MEN1KMT2APKMKDM4E
	SCHEMBL1018706	0.87	ACACB (0.43)	ALDH1A1MEN1KMT2APKMKDM4E
	SCHEMBL1017932	0.86	MAPT (0.44)	ALDH1A1MEN1KMT2APKMKDM4E
	SCHEMBL1018776	0.85	HRH3 (0.41)	ALDH1A1MEN1KMT2APKMKDM4E
	SCHEMBL1014831	0.85	PRMT5 (0.46)	ALDH1A1MEN1KMT2APKMKDM4E
	SCHEMBL1018762	0.85	RAB9A (0.45)	ALDH1A1MEN1KMT2APKMKDM4E
	SCHEMBL1017737	0.85	HRH3 (0.46)	ALDH1A1MEN1KMT2APKMKDM4E
	SCHEMBL1604050	0.85	ALDH1A1 (0.50)	ALDH1A1KMT2AKDM4EHRH3GAA
	SCHEMBL1020441	0.85	ALDH1A1 (0.50)	ALDH1A1KMT2AKDM4EHRH3GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.