SCHEMBL1017172

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1018389	0.94	HRH3 (0.46)	KDM2BHTTNPSR1HRH3ALDH1A1
	SCHEMBL1016580	0.92	HTT (0.43)	KDM2BHTTNPSR1HRH3L3MBTL3
	SCHEMBL1018194	0.90	ALDH1A1 (0.45)	KDM2BHRH3ALDH1A1GAAPKM
	SCHEMBL1017674	0.90	KDM2B (0.44)	KDM2BHTTNPSR1L3MBTL3L3MBTL1
	SCHEMBL1020245	0.90	HRH3 (0.44)	KDM2BHRH3L3MBTL3L3MBTL1ALDH1A1
	SCHEMBL1017100	0.89	HRH3 (0.54)	KDM2BHRH3L3MBTL3L3MBTL1ALDH1A1
	SCHEMBL1017944	0.89	ACACB (0.47)	KDM2BHRH3L3MBTL3L3MBTL1ALDH1A1
	SCHEMBL1014264	0.89	ALDH1A1 (0.40)	KDM2BALDH1A1GAAPKMHSD17B10
	SCHEMBL1017553	0.88	HRH3 (0.50)	HRH3L3MBTL3L3MBTL1ALDH1A1
	SCHEMBL12953761	0.88	HDAC6 (0.43)	KDM2BHRH3L3MBTL3L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.