SCHEMBL1017674

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1017172	0.90	KDM2B (0.45)	KDM2BL3MBTL3L3MBTL1HTTNPSR1
	SCHEMBL1018279	0.86	TP53 (0.48)	PRMT5WDR77TP53
	SCHEMBL1020289	0.85	KDM2B (0.39)	KDM2BKMT2APRMT5WDR77
	SCHEMBL1018389	0.83	HRH3 (0.46)	KDM2BPOLBHTTNPSR1
	SCHEMBL1018774	0.83	KDM2B (0.38)	KDM2BL3MBTL3L3MBTL1KMT2APRMT5
	SCHEMBL12707114	0.83	KDM2B (0.38)	KDM2BL3MBTL3L3MBTL1KMT2APRMT5
	SCHEMBL1016580	0.82	HTT (0.43)	KDM2BL3MBTL3L3MBTL1PRMT5WDR77
	SCHEMBL1014264	0.81	ALDH1A1 (0.40)	KDM2BKMT2APRMT5WDR77POLB
	SCHEMBL1017628	0.81	HRH3 (0.42)	PRMT5WDR77TP53
	SCHEMBL1017553	0.81	HRH3 (0.50)	L3MBTL3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.