Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HRAS | P01112 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20058768 | 0.87 | MAPT (0.40) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL881707 | 0.85 | P2RY11 (0.39) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL24791256 | 0.83 | NPC1 (0.39) | POLBMEN1KMT2AALDH1A1EGFR | |
| SCHEMBL24917290 | 0.80 | MAPT (0.36) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL881416 | 0.80 | MAPT (0.36) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL882455 | 0.79 | MAPT (0.39) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL881488 | 0.79 | MEN1 (0.47) | POLBMEN1USP2KMT2AP2RX3 | |
| SCHEMBL18214662 | 0.77 | MAPT (0.40) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL18697570 | 0.77 | MAPT (0.41) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL882017 | 0.76 | TMPRSS2 (0.39) | MAPTPOLBMEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012039787-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-29 | — | — | WO | disclosed |