Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
| ▸ | HRAS | P01112 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18214662 | 0.90 | MAPT (0.40) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL10171930 | 0.87 | MAPT (0.41) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL882017 | 0.87 | TMPRSS2 (0.39) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL18214621 | 0.80 | TMPRSS2 (0.39) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL24791260 | 0.80 | ALDH1A1 (0.36) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL17617320 | 0.80 | ALDH1A1 (0.36) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL14996153 | 0.80 | ALDH1A1 (0.36) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL881372 | 0.80 | ALDH1A1 (0.36) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL10171966 | 0.79 | ALDH1A1 (0.36) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL25914985 | 0.79 | ALDH1A1 (0.38) | ALDH1A1RIPK1TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906579-B1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-04-18 | — | — | EP | disclosed |