Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HRAS | P01112 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882455 | 0.92 | MAPT (0.39) | P2RY11MAPTKMT2AMEN1USP2 | |
| SCHEMBL10171930 | 0.85 | MAPT (0.41) | P2RY11MAPTKMT2AMEN1USP2 | |
| SCHEMBL10148643 | 0.82 | P2RY11 (0.37) | P2RY11MAPTKMT2AMEN1USP2 | |
| SCHEMBL10149715 | 0.82 | P2RY11 (0.37) | P2RY11MAPTKMT2AMEN1USP2 | |
| SCHEMBL12836612 | 0.80 | MAPT (0.35) | P2RY11MAPTKMT2AMEN1USP2 | |
| SCHEMBL10171929 | 0.77 | NPC1 (0.35) | P2RY11MAPTKMT2AMEN1POLB | |
| SCHEMBL20058768 | 0.76 | MAPT (0.40) | MAPTKMT2AMEN1USP2POLB | |
| SCHEMBL10186058 | 0.74 | MAPT (0.35) | P2RY11MAPTKMT2AMEN1USP2 | |
| SCHEMBL12398065 | 0.74 | MAPT (0.35) | P2RY11MAPTKMT2AMEN1USP2 | |
| SCHEMBL881368 | 0.74 | MAPT (0.35) | P2RY11MAPTKMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012039787-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-29 | — | — | WO | disclosed |