SCHEMBL10172885

SCHEMBL10172885

C1=CCC(N(c2ccccc2)c2ccccc2)CC1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
CCR5 P51681 2/20 0.32
OPRM1 P35372 1/20 0.32
OPRD1 P41143 1/20 0.32
KCNA3 P22001 1/20 0.32
CYP3A4 P08684 1/20 0.31
HTR7 P34969 1/20 0.31
HTT P42858 1/20 0.31
FAAH O00519 1/20 0.31
PHGDH O43175 1/20 0.31
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13670997 0.84 RELA (0.37) KDM4ESLC6A2SLC6A4OPRM1OPRD1
SCHEMBL15256650 0.83 SLC6A2 (0.30) SLC6A2SLC6A4
SCHEMBL22754703 0.77 SLC6A2 (0.32) SLC6A2SLC6A4OPRM1OPRD1HTT
SCHEMBL7701226 0.77 SLC6A2 (0.41) SLC6A2SLC6A4CCR5OPRM1OPRD1
SCHEMBL14640497 0.75 SLC6A2 (0.45) SLC6A2SLC6A4CCR5OPRM1OPRD1
SCHEMBL11788207 0.75 SLC6A2 (0.45) SLC6A2SLC6A4CCR5OPRM1OPRD1
SCHEMBL30036856 0.73 KCNA3 (0.47) KDM4ESLC6A2SLC6A4CCR5OPRM1
Hydrochloric Acid SCHEMBL11789965 0.73 SLC6A2 (0.44) SLC6A2SLC6A4CCR5OPRM1OPRD1
SCHEMBL218047 0.72 KCNA3 (0.50) KDM4EHSD17B10SLC6A2SLC6A4CCR5
SCHEMBL616634 0.70 KCNA3 (0.53) KDM4EHSD17B10SLC6A2SLC6A4CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2418033-A1 METAL COMPLEX AND COMPOSITION CONTAINING SAME Sumitomo Chemical Company, Limited (JP) 2012-02-15 EP disclosed