SCHEMBL616634

SCHEMBL616634

c1ccc(N(c2ccccc2)C2CCCCC2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.53
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 2/20 0.49
NPC1 O15118 1/20 0.49
MITF O75030 1/20 0.49
RAB9A P51151 1/20 0.49
PAX8 Q06710 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
CYP3A4 P08684 1/20 0.47
ESR1 P03372 1/20 0.45
TRPM8 Q7Z2W7 1/20 0.45
CCR5 P51681 2/20 0.44
G6PC1 P35575 1/20 0.42
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
ATM Q13315 1/20 0.41
USP2 O75604 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11484964 0.98 KCNA3 (0.51) KCNA3MEN1KMT2AKDM4EALDH1A1
SCHEMBL218047 0.98 KCNA3 (0.50) KCNA3MEN1KMT2AKDM4EALDH1A1
SCHEMBL30036856 0.95 KCNA3 (0.47) KCNA3MEN1KMT2AKDM4EALDH1A1
SCHEMBL14817427 0.92 KCNA3 (0.48) KCNA3MEN1KMT2AKDM4EALDH1A1
SCHEMBL4476845 0.90 KCNA3 (0.47) KCNA3MEN1KMT2AKDM4EALDH1A1
SCHEMBL852761 0.88 CYP3A4 (0.50) KCNA3MEN1KMT2AKDM4EALDH1A1
SCHEMBL11636825 0.88 KCNA3 (0.46) KCNA3MEN1KMT2AKDM4EALDH1A1
SCHEMBL29332538 0.88 ESR1 (0.56) KCNA3MEN1KMT2AKDM4EALDH1A1
SCHEMBL11788207 0.87 SLC6A2 (0.45) KCNA3MEN1KMT2AALDH1A1CYP3A4
SCHEMBL14640497 0.87 SLC6A2 (0.45) KCNA3MEN1KMT2AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115286657-A Continuous production method of hydroxymethyl phosphonate 湖北理工学院 2022-11-04 CN claimed
US-9187504-B2 Method of making hydroxymethylphosphonate ICL-IP AMERICA INC. (US) 2015-11-17 US claimed
EP-2376507-B1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATES ICL IP AMERICA INC (US) 2013-05-15 EP claimed
US-8198341-B2 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom ICL-IP AMERICA INC. (US) 2012-06-12 US claimed
US-20110257287-A1 Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom STOWELL JEFFREY K 2011-10-20 US claimed
EP-2376507-A1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS POLYURETHANE FOAM AND ARTICLES MADE THEREFORM ICL-IP America Inc. (US) 2011-10-19 EP claimed
WO-2010080425-A1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS POLYURETHANE FOAM AND ARTICLES MADE THEREFORM SUPRESTA LLC. (US) 2010-07-15 WO claimed
US-20100160468-A1 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom ICL-IP AMERICA INC. 2010-06-24 US claimed
US-5147621-A Amine stabilizer CHEMIE AG BITTERFELD-WOLFEN (DE) 1992-09-15 US claimed
JP-5247051-A None JP disclosed
CN-114436861-B Compound and organic electroluminescent device 阜阳欣奕华新材料科技股份有限公司 2024-11-15 CN disclosed
US-20240240024-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN LAYER USING THE SAME, AND COLOR FILTER SAMSUNG SDI CO., LTD. (KR) 2024-07-18 US disclosed
US-20240240024-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN LAYER USING THE SAME, AND COLOR FILTER SAMSUNG SDI CO., LTD. (KR) 2024-07-18 US disclosed
CN-116925111-A Organic compound and application thereof 北京鼎材科技有限公司 2023-10-24 CN disclosed
US-4452943-A ADDING NITRILE-CONTAINING MATERIAL TO NON-POLAR THERMOPLASTIC POLYMER GOLDMAN CONRAD 1984-06-05 US disclosed
US-4448869-A HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE FUJI PHOTO FILM CO., LTD. (JP) 1984-05-15 US disclosed
US-4447515-A DIACYLAMINE COMPOUND ADDED FUJI PHOTO FILM CO., LTD. (JP) 1984-05-08 US disclosed
US-4444863-A UREA COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1984-04-24 US disclosed
US-4387149-A CATIONIC DYES; STABILITY; COPYING MITSUBISHI PAPER MILLS, LTD. (JP) 1983-06-07 US disclosed
EP-0014998-A1 Preparation of tertiary aromatic amines by reductive alkylation of diaryl secondary amines with ketones UNIROYAL, INC. (US) 1980-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110257287-A1 Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom PFAS, PGM2, NEFM KCNA3 3221/4885MEN1 3375/4885KMT2A 2045/4885
US-20100160468-A1 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom PFAS, PGM2, NEFM KCNA3 3221/4885MEN1 3375/4885KMT2A 2045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.