SCHEMBL1017314

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1018047	0.86	ACHE (0.47)	KDM2BPARP1PRMT5WDR77ALDH1A1
	SCHEMBL1016153	0.85	ALDH1A1 (0.48)	USP30PARP1ALDH1A1GAAPKM
	SCHEMBL1017531	0.85	CD274 (0.44)	KDM2BPARP1PRMT5WDR77ALDH1A1
	SCHEMBL1015291	0.84	ACHE (0.47)	KDM2BPARP1PRMT5WDR77ALDH1A1
	SCHEMBL1016929	0.83	CD274 (0.48)	PARP1ALDH1A1GAAPKMHSD17B10
	SCHEMBL1016365	0.83	HRH3 (0.46)	PARP1PRMT5WDR77ALDH1A1GAA
	SCHEMBL1016764	0.83	CD274 (0.40)	PARP1PRMT5WDR77ALDH1A1GAA
	SCHEMBL1016795	0.83	MEN1 (0.50)	ALDH1A1GAAPKMHSD17B10KDM4E
	SCHEMBL1014859	0.83	KDM4E (0.50)	PARP1ALDH1A1GAAPKMHSD17B10
	SCHEMBL1019934	0.83	PRMT5 (0.42)	USP30PARP1PRMT5WDR77ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.