Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 6/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3080514 | 1.00 | RAB9A (0.44) | RAB9AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3088580 | 1.00 | RAB9A (0.44) | RAB9AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5624115 | 0.94 | RAB9A (0.39) | RAB9AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1018516 | 0.89 | GRM5 (0.45) | ALDH1A1CHRNA7BCHEACHEOGA | |
| SCHEMBL1018366 | 0.84 | GAA (0.42) | ALDH1A1CHRNA7BCHEACHEOGA | |
| SCHEMBL3085002 | 0.82 | CHRNA7 (0.43) | CHRNA7LSSCHRM2 | |
| SCHEMBL1020348 | 0.82 | CHRNA7 (0.43) | CHRNA7LSSCHRM2 | |
| SCHEMBL3073508 | 0.82 | CHRNA7 (0.43) | CHRNA7LSSCHRM2 | |
| SCHEMBL1018510 | 0.82 | LSS (0.48) | RAB9ACHRNA7NPC1LSSCHRM2 | |
| SCHEMBL1019786 | 0.82 | CHRNA7 (0.44) | CHRNA7LSSCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802616-B1 | NOVEL AZABICYCLIC ARYL DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH AS (DK) | 2011-01-12 | — | — | EP | claimed |
| US-20100227869-A1 | ENANTIOPURE QUINUCLIDINYLOXY PYRIDAZINES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2010-09-09 | — | — | US | claimed |
| US-7652010-B2 | Azabicyclic aryl derivatives and their medical use | NEUROSEARCH A/S (DK) | 2010-01-26 | — | — | US | claimed |
| EP-1987029-B1 | ENANTIOPURE QUINUCLIDINYLOXY PYRIDAZINES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | NEUROSEARCH AS (DK) | 2010-01-13 | — | — | EP | claimed |
| US-20070299082-A1 | Novel Azabicyclic Aryl Derivatives and Their Medical Use | ANIONA APS (DK) | 2007-12-27 | — | — | US | claimed |
| EP-1802616-B1 | NOVEL AZABICYCLIC ARYL DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH AS (DK) | 2011-01-12 | — | — | EP | disclosed |
| US-20100227869-A1 | ENANTIOPURE QUINUCLIDINYLOXY PYRIDAZINES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2010-09-09 | — | — | US | disclosed |
| US-7652010-B2 | Azabicyclic aryl derivatives and their medical use | NEUROSEARCH A/S (DK) | 2010-01-26 | — | — | US | disclosed |
| EP-1987029-B1 | ENANTIOPURE QUINUCLIDINYLOXY PYRIDAZINES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | NEUROSEARCH AS (DK) | 2010-01-13 | — | — | EP | disclosed |
| US-20070299082-A1 | Novel Azabicyclic Aryl Derivatives and Their Medical Use | ANIONA APS (DK) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299082-A1 | Novel Azabicyclic Aryl Derivatives and Their Medical Use | CHRNA6, CHRNA10, CHRNA5 | RAB9A 2617/4885MEN1 4620/4885KMT2A 1559/4885 |
| US-20100227869-A1 | ENANTIOPURE QUINUCLIDINYLOXY PYRIDAZINES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | CHRNA5, CHRNA6, CHRNA2 | RAB9A 2290/4885MEN1 4266/4885KMT2A 3094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.