Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20841466 | 0.78 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL14878228 | 0.77 | LMNA (0.44) | MAPTALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL8508926 | 0.77 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL10176070 | 0.77 | MAPT (0.39) | MAPTALDH1A1MEN1KMT2AUSP2 | |
| Fluorescein Diacetate SCHEMBL1028369 | 0.74 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AUSP2 | |
| Fluorescein Diacetate SCHEMBL29353816 | 0.74 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AUSP2 | |
| Fluorescein Diacetate SCHEMBL31658971 | 0.74 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AUSP2 | |
| Fluorescein Diacetate SCHEMBL29453229 | 0.74 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AUSP2 | |
| Fluorescein Diacetate SCHEMBL7648940 | 0.73 | MAPT (0.98) | MAPTALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL14030642 | 0.73 | MAPT (0.40) | MAPTALDH1A1MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114904-B2 | Luminescence quenchers and fluorogenic probes for detection of reactive species | Versitech Limited & Morningside Ventures Limited (CN) | 2012-02-14 | — | — | US | disclosed |