Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10176069 | 0.77 | MAPT (0.58) | MAPTLMNAALDH1A1HTTMEN1 | |
| SCHEMBL10176071 | 0.75 | MAPT (0.36) | MAPTLMNAALDH1A1HTTMEN1 | |
| SCHEMBL29349570 | 0.71 | MAPT (0.66) | MAPTLMNAALDH1A1HTTMEN1 | |
| SCHEMBL1024927 | 0.71 | MAPT (0.66) | MAPTLMNAALDH1A1HTTMEN1 | |
| SCHEMBL15349331 | 0.69 | GSTP1 (0.48) | MAPTLMNAALDH1A1HTTMEN1 | |
| SCHEMBL12288857 | 0.67 | LMNA (0.38) | MAPTLMNAALDH1A1HTTMEN1 | |
| SCHEMBL10100294 | 0.67 | MAPT (0.53) | MAPTLMNAALDH1A1HTTMEN1 | |
| SCHEMBL13914125 | 0.66 | MAPT (0.68) | MAPTLMNAALDH1A1HTTMEN1 | |
| SCHEMBL10145450 | 0.66 | MAPT (0.58) | MAPTLMNAALDH1A1HTTMEN1 | |
| SCHEMBL18184153 | 0.66 | MAPT (0.58) | MAPTLMNAALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114904-B2 | Luminescence quenchers and fluorogenic probes for detection of reactive species | Versitech Limited & Morningside Ventures Limited (CN) | 2012-02-14 | — | — | US | disclosed |