Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL640612 | 0.84 | CA1 (0.45) | SMN1; SMN2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL10176139 | 0.84 | ALDH1A1 (0.48) | SMN1; SMN2HTTKDM4EALDH1A1HPGD | |
| SCHEMBL4100380 | 0.83 | CSNK2A2 (0.46) | CSNK2A2CSNK2BCSNK2A1CSNK2A3OGA | |
| SCHEMBL3493311 | 0.81 | ALDH1A1 (0.48) | SMN1; SMN2MAPK1CSNK2A2CSNK2A1POLB | |
| SCHEMBL7019955 | 0.81 | CSNK2A2 (0.47) | SMN1; SMN2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL2655832 | 0.80 | L3MBTL1 (0.56) | SMN1; SMN2MAPK1CSNK2A2CSNK2A1KDM4E | |
| SCHEMBL13696381 | 0.80 | CSNK2A2 (0.38) | SMN1; SMN2MAPK1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL10226204 | 0.79 | CSNK2A2 (0.46) | SMN1; SMN2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL10227543 | 0.79 | CSNK2A2 (0.46) | SMN1; SMN2CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL15947709 | 0.79 | CA12 (0.47) | SMN1; SMN2HTTPOLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119812-B2 | Thiazolidinone derivative | SBI BIOTECH CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-8119812-B2 | Thiazolidinone derivative | SBI BIOTECH CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| WO-2010122979-A1 | THIAZOLIDINONE DERIVATIVE | ＳＢＩバイオテック株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | CDC7, CDK17, CDCA2 | SMN1; SMN2 4601/4885MAPK1 1399/4885CSNK2A2 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.