⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145537 | 0.84 | MAPT (0.41) | — | |
| SCHEMBL10145602 | 0.74 | MAPT (0.43) | — | |
| SCHEMBL10145698 | 0.74 | MAPT (0.43) | — | |
| SCHEMBL10145610 | 0.74 | MEN1 (0.46) | — | |
| SCHEMBL10145700 | 0.67 | MAPT (0.44) | — | |
| SCHEMBL10145477 | 0.66 | MAPT (0.52) | — | |
| SCHEMBL10145706 | 0.66 | MAPT (0.43) | — | |
| SCHEMBL13648698 | 0.65 | MAPT (0.43) | — | |
| SCHEMBL10145608 | 0.64 | MAPT (0.49) | — | |
| SCHEMBL10176070 | 0.64 | MAPT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114904-B2 | Luminescence quenchers and fluorogenic probes for detection of reactive species | Versitech Limited & Morningside Ventures Limited (CN) | 2012-02-14 | — | — | US | disclosed |