Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL883089 | 0.98 | CHRNB2 (0.38) | CHRNB2CHRNA7CHRNA4SCN10AMKNK1 | |
| SCHEMBL882749 | 0.98 | CHRNB2 (0.38) | CHRNB2CHRNA7CHRNA4SCN10AMKNK1 | |
| SCHEMBL15105935 | 0.98 | CHRNB2 (0.38) | CHRNB2CHRNA7CHRNA4SCN10AMKNK1 | |
| SCHEMBL17401124 | 0.93 | KCNH2 (0.37) | CHRNB2CHRNA7CHRNA4SCN10AMKNK1 | |
| SCHEMBL1981541 | 0.93 | CDC7 (0.40) | CHRNB2CHRNA7CHRNA4SCN10AMKNK1 | |
| SCHEMBL12682669 | 0.93 | MKNK1 (0.40) | CHRNB2CHRNA7CHRNA4SCN10AMKNK1 | |
| SCHEMBL2683531 | 0.93 | CDC7 (0.40) | CHRNB2CHRNA7CHRNA4SCN10AMKNK1 | |
| SCHEMBL12682632 | 0.93 | CYP1A2 (0.40) | CHRNB2CHRNA7CHRNA4SCN10AMKNK1 | |
| SCHEMBL12682719 | 0.93 | SCN10A (0.35) | CHRNB2CHRNA7CHRNA4SCN10AMKNK1 | |
| SCHEMBL18498321 | 0.93 | KCNH2 (0.37) | CHRNB2CHRNA7CHRNA4SCN10AMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115855-A1 | INHIBITORS OF HCV NS5A | PRESIDIO PHARMACEUTICALS, INC. (US) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115855-A1 | INHIBITORS OF HCV NS5A | HAVCR2, MAVS, EIF2AK2 | CHRNB2 4853/4885CHRNA7 4838/4885CHRNA4 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.