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SCHEMBL10177705

SCHEMBL10177705

O=C(OCC1OC(OC2C(COC(=O)c3ccccc3)OC(OC(=O)c3ccccc3)C(OC(=O)c3ccccc3)C2OC(=O)c2ccccc2)C(OC(=O)c2ccccc2)C(OC(=O)c2ccccc2)C1OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ANTXR2 P58335 3/20 0.61
▸ PTPN1 P18031 4/20 0.61
▸ F11 P03951 2/20 0.56
▸ USP2 O75604 2/20 0.56
▸ CA1 P00915 2/20 0.56
▸ CA2 P00918 2/20 0.56
▸ TMPRSS2 O15393 1/20 0.56
▸ PDE5A O76074 1/20 0.56
▸ HMGCR P04035 1/20 0.56
▸ CYP1A2 P05177 1/20 0.56
▸ LCK P06239 1/20 0.56
▸ FYN P06241 1/20 0.56
▸ HSPD1 P10809 1/20 0.56
▸ CYP2C9 P11712 1/20 0.56
▸ CA6 P23280 1/20 0.56
▸ TBXAS1 P24557 1/20 0.56
▸ MAPK3 P27361 1/20 0.56
▸ MAPK1 P28482 1/20 0.56
▸ HSPE1 P61604 1/20 0.56
▸ MAPK14 Q16539 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8952214 1.00 ANTXR2 (0.61) ANTXR2PTPN1F11USP2CA1
SCHEMBL2816580 1.00 ANTXR2 (0.61) ANTXR2PTPN1F11USP2CA1
SCHEMBL12172394 1.00 ANTXR2 (0.61) ANTXR2PTPN1F11USP2CA1
SCHEMBL19038896 1.00 ANTXR2 (0.61) ANTXR2PTPN1F11USP2CA1
SCHEMBL1322250 1.00 ANTXR2 (0.61) ANTXR2PTPN1F11USP2CA1
SCHEMBL2814863 1.00 ANTXR2 (0.61) ANTXR2PTPN1F11USP2CA1
SCHEMBL13024918 0.97 PTPN1 (0.61) ANTXR2PTPN1F11USP2CA1
SCHEMBL3785587 0.95 PTPN1 (0.67) ANTXR2PTPN1F11USP2CA1
SCHEMBL18083458 0.95 PTPN1 (0.67) ANTXR2PTPN1F11USP2CA1
SCHEMBL19479105 0.95 PTPN1 (0.67) ANTXR2PTPN1F11USP2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11666653-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2023-06-06 — — US disclosed
US-20220143189-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES BANK OF AMERICA, N.A. 2022-05-12 — — US disclosed
US-11110174-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2021-09-07 — — US disclosed
US-20200297853-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES BANK OF AMERICA, N.A. 2020-09-24 — — US disclosed
US-9814777-B2 Targeting lipids ARBUTUS BIOPHARMA CORPORATION (CA) 2017-11-14 — — US disclosed
EP-3156077-A1 TARGETING LIPIDS Arbutus Biopharma Corporation (CA) 2017-04-19 — — EP disclosed
EP-2231195-B1 TARGETING LIPIDS ARBUTUS BIOPHARMA CORP (CA) 2017-03-29 — — EP disclosed
US-9352048-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2016-05-31 — — US disclosed
US-20150119445-A1 Carbohydrate Conjugates as Delivery Agents for Oligonucleotides BANK OF AMERICA, N.A. 2015-04-30 — — US disclosed
US-20150011615-A1 Carbohydrate Conjugates as Delivery Agents for Oligonucleotides BANK OF AMERICA, N.A. 2015-01-08 — — US disclosed
US-8828956-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2014-09-09 — — US disclosed
US-20140179761-A1 TARGETING LIPIDS TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2014-06-26 — — US disclosed
US-20130178512-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC (US) 2013-07-11 — — US disclosed
US-8450467-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2013-05-28 — — US disclosed
US-8106022-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2012-01-31 — — US disclosed
WO-2009082607-A2 TARGETING LIPIDS ALNYLAM PHARMACEUTICALS, INC. (US) 2009-07-02 — — WO disclosed
WO-2009073809-A2 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2009-06-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130178512-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES LPXN, ZYX, OSTC ANTXR2 2183/4885PTPN1 1551/4885F11 1343/4885
US-20150119445-A1 Carbohydrate Conjugates as Delivery Agents for Oligonucleotides LPXN, ZYX, OSTC ANTXR2 2132/4885PTPN1 1472/4885F11 1353/4885
US-20140179761-A1 TARGETING LIPIDS LY96, ABHD10, APOB ANTXR2 563/4885PTPN1 3225/4885F11 1817/4885
US-20200297853-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES SLC2A2, SLC2A8, SLC2A1 ANTXR2 619/4885PTPN1 2198/4885F11 881/4885
US-11666653-B2 Carbohydrate conjugates as delivery agents for oligonucleotides HAVCR2, B3GAT3, CSGALNACT1 ANTXR2 396/4885PTPN1 2680/4885F11 3371/4885
US-20150011615-A1 Carbohydrate Conjugates as Delivery Agents for Oligonucleotides LPXN, ZYX, OSTC ANTXR2 2149/4885PTPN1 1542/4885F11 1300/4885
US-20220143189-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES HAVCR2, B3GAT3, CSGALNACT1 ANTXR2 396/4885PTPN1 2680/4885F11 3371/4885
US-11110174-B2 Carbohydrate conjugates as delivery agents for oligonucleotides SLC2A2, SLC2A8, SLC2A1 ANTXR2 619/4885PTPN1 2198/4885F11 881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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