Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 7/20 | 0.34 |
| ▸ | CDC25A | P30304 | 5/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15978370 | 1.00 | DUSP3 (0.34) | DUSP3CDC25AMAPKAPK2PTPN1 | |
| SCHEMBL15978305 | 0.73 | MAPKAPK2 (0.49) | DUSP3CDC25AMAPKAPK2PTPN1 | |
| SCHEMBL2426248 | 0.69 | TSHR (0.34) | — | |
| SCHEMBL2426256 | 0.69 | TSHR (0.34) | — | |
| SCHEMBL2427497 | 0.64 | ALOX15 (0.38) | — | |
| SCHEMBL2921250 | 0.58 | DUSP3 (0.56) | DUSP3CDC25AMAPKAPK2PTPN1 | |
| SCHEMBL19214454 | 0.58 | DUSP3 (0.56) | DUSP3CDC25AMAPKAPK2PTPN1 | |
| SCHEMBL15886618 | 0.57 | DUSP3 (0.58) | DUSP3CDC25AMAPKAPK2PTPN1 | |
| SCHEMBL2982726 | 0.57 | DUSP3 (0.58) | DUSP3CDC25AMAPKAPK2PTPN1 | |
| SCHEMBL1791881 | 0.54 | USP2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037069-A2 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-03-22 | — | — | WO | disclosed |