Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2426248 | 1.00 | TSHR (0.34) | TSHRMAPK1 | |
| SCHEMBL2426251 | 1.00 | TSHR (0.34) | TSHRMAPK1 | |
| SCHEMBL2426817 | 0.77 | TSHR (0.37) | TSHRMAPK1 | |
| SCHEMBL2426813 | 0.77 | TSHR (0.37) | TSHRMAPK1 | |
| SCHEMBL2426815 | 0.77 | TSHR (0.37) | TSHRMAPK1 | |
| SCHEMBL29403609 | 0.72 | TSHR (0.34) | TSHRMAPK1 | |
| SCHEMBL29402647 | 0.72 | TSHR (0.34) | TSHRMAPK1 | |
| SCHEMBL2427497 | 0.70 | ALOX15 (0.38) | — | |
| SCHEMBL10178504 | 0.69 | DUSP3 (0.34) | — | |
| SCHEMBL2863012 | 0.69 | TSHR (0.32) | TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222198-B2 | Perfuming nitriles | FIRMENICH SA (CH) | 2012-07-17 | — | — | US | disclosed |
| EP-2134318-B1 | PERFUMING NITRILES | FIRMENICH & CIE (CH) | 2011-09-07 | — | — | EP | disclosed |
| US-20100267607-A1 | PERFUMING NITRILES | FIRMENICH SA (CH) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267607-A1 | PERFUMING NITRILES | TRPA1, NIT2, PNN | TSHR 4517/4885MAPK1 3432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.