SCHEMBL10178628

SCHEMBL10178628

CCC(C)c1cccc(COCc2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
HDAC4 P56524 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
BCHE P06276 2/20 0.43
TACR1 P25103 8/20 0.42
APP P05067 1/20 0.38
ALOX5 P09917 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14119488 0.89 KCNH2 (0.46) TSHRHDAC4HDAC2HDAC8TACR1
SCHEMBL10178623 0.88 HDAC4 (0.46) TSHRHDAC4HDAC2HDAC8BCHE
SCHEMBL10178438 0.84 TSHR (0.56) TSHRBCHETACR1ALOX5
SCHEMBL19445349 0.84 HDAC4 (0.43) HDAC4HDAC2HDAC8BCHETACR1
SCHEMBL10178653 0.84 BCHE (0.53) BCHEALOX5
SCHEMBL14461736 0.83 HDAC4 (0.43) HDAC4HDAC2HDAC8
SCHEMBL10178568 0.83 HDAC4 (0.47) HDAC4HDAC2HDAC8BCHE
SCHEMBL26162716 0.81 TSHR (0.52) TSHRTACR1
SCHEMBL11922929 0.81 BCHE (0.60) BCHEALOX5
SCHEMBL28346872 0.81 BCHE (0.60) BCHEALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124310-B2 Positive resist composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-20090087784-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed