Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443416 | 0.87 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TSHRKDM4EUSP2 | |
| SCHEMBL159682 | 0.78 | ALDH1A1 (0.34) | ALDH1A1HSD17B10TSHRKDM4EUSP2 | |
| SCHEMBL1440099 | 0.78 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TSHR | |
| SCHEMBL2436675 | 0.77 | — | — | |
| SCHEMBL12302082 | 0.76 | ALDH1A1 (0.30) | ALDH1A1HSD17B10TSHR | |
| SCHEMBL1444213 | 0.76 | NOTUM (0.43) | ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL1444215 | 0.76 | — | — | |
| SCHEMBL22721355 | 0.75 | TSHR (0.60) | ALDH1A1HSD17B10TSHR | |
| SCHEMBL1439941 | 0.73 | IDO1 (0.32) | ALDH1A1KDM4E | |
| SCHEMBL14537548 | 0.73 | KDM4E (0.36) | ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473474-A2 | FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF | E. I. du Pont de Nemours and Company (US) | 2012-07-11 | — | — | EP | disclosed |