SCHEMBL159682

SCHEMBL159682

O=C(O)c1ccc(C(=O)O)c(OC(F)(F)C(F)OC(F)(F)C(F)(OC(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
TSHR P16473 2/20 0.34
HSD17B10 Q99714 2/20 0.34
KDM4E B2RXH2 2/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
ACE2 Q9BYF1 1/20 0.31
PYGL P06737 1/20 0.31
USP2 O75604 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA7 P43166 1/20 0.30
TPMT P51580 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12302082 0.93 ALDH1A1 (0.30) ALDH1A1TSHRHSD17B10
SCHEMBL1443416 0.91 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10KDM4EGAA
SCHEMBL158558 0.86
SCHEMBL175588 0.84 KDM4E (0.40) ALDH1A1HSD17B10KDM4EGAAHPGD
SCHEMBL1440259 0.83 MAPT (0.33) ALDH1A1KDM4E
SCHEMBL158941 0.83 KDM4E (0.32) ALDH1A1TSHRHSD17B10KDM4EGAA
SCHEMBL15675519 0.83 ALDH1A1 (0.52) ALDH1A1TSHRHSD17B10CA1CA2
SCHEMBL160267 0.82 PYGL (0.35) ALDH1A1TSHRHSD17B10KDM4EGAA
SCHEMBL158679 0.81 ALDH1A1 (0.37) ALDH1A1TSHRHSD17B10
SCHEMBL2436675 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2611855-A1 POLYARAMID FILMS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E.I. Du Pont De Nemours And Company (US) 2013-07-10 EP disclosed
US-8350099-B2 Fluorovinyl ether functionalized aromatic diesters, derivatives thereof, and process for the preparation thereof E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-08 US disclosed
US-8350099-B2 Fluorovinyl ether functionalized aromatic diesters, derivatives thereof, and process for the preparation thereof E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-08 US disclosed
US-8350099-B2 Fluorovinyl ether functionalized aromatic diesters, derivatives thereof, and process for the preparation thereof E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-08 US disclosed
US-8304513-B2 Polyesters comprising fluorovinylether functionalized aromatic moieties E I DU PONT DE NEMOURS AND COMPANY (US) 2012-11-06 US disclosed
EP-2473547-A2 POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. du Pont de Nemours and Company (US) 2012-07-11 EP disclosed
EP-2473543-A2 POLYESTERS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. du Pont de Nemours and Company (US) 2012-07-11 EP disclosed
EP-2473474-A2 FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF E. I. du Pont de Nemours and Company (US) 2012-07-11 EP disclosed
WO-2012030352-A1 POLYARAMID FILMS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-03-08 WO disclosed
WO-2012030352-A1 POLYARAMID FILMS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-03-08 WO disclosed
US-20110218317-A1 POLYESTERS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-08 US disclosed
US-20110218319-A1 POLYARAMID FILMS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-08 US disclosed
US-20110218319-A1 POLYARAMID FILMS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-08 US disclosed
US-20110213118-A1 POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-01 US disclosed
US-20110213118-A1 POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-01 US disclosed
US-20110213118-A1 POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-01 US disclosed
WO-2011028791-A2 POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-10 WO disclosed
WO-2011028791-A2 POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-10 WO disclosed
WO-2011028778-A2 POLYESTERS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-10 WO disclosed
WO-2011028767-A2 FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-10 WO disclosed