SCHEMBL10179515

SCHEMBL10179515

CC(C)(C)c1ccc(S(=O)(=O)CC(F)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.52
CA1 P00915 3/20 0.49
CA2 P00918 3/20 0.49
LMNA P02545 2/20 0.47
GAA P10253 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
POLB P06746 1/20 0.45
RECQL P46063 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.43
TP53 P04637 1/20 0.43
HSD11B1 P28845 2/20 0.43
RORA P35398 1/20 0.43
HTT P42858 2/20 0.42
USP2 O75604 1/20 0.42
ALOX15 P16050 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ACHE P22303 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10181139 0.84 ALDH1A1 (0.42) ALDH1A1CA1CA2LMNAGAA
SCHEMBL3256579 0.79 ALDH1A1 (0.59) ALDH1A1CA1CA2LMNAGAA
SCHEMBL9906397 0.79 ALDH1A1 (0.59) ALDH1A1CA1CA2LMNAGAA
SCHEMBL10179540 0.79 CYP3A4 (0.50) ALDH1A1CA1CA2GAAMEN1
SCHEMBL776676 0.78 ALDH1A1 (0.43) ALDH1A1CA1CA2MEN1KMT2A
SCHEMBL15121175 0.77 CA1 (0.50) ALDH1A1CA1CA2MEN1KMT2A
SCHEMBL12005156 0.77 ALDH1A1 (0.43) ALDH1A1CA1CA2LMNAGAA
SCHEMBL10181399 0.77 CA2 (0.52) ALDH1A1CA2GAAMEN1KMT2A
SCHEMBL23501536 0.76 GAA (0.55) ALDH1A1CA1CA2LMNAGAA
SCHEMBL3109115 0.76 PLCG1 (0.59) ALDH1A1CA1CA2LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed