Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.41 |
| ▸ | UBE2M | P61081 | 5/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1017954 | 1.00 | SLC2A1 (0.42) | SLC2A1DCUN1D1UBE2MACKR3KMT2A | |
| SCHEMBL12955051 | 0.96 | ACKR3 (0.42) | DCUN1D1UBE2MACKR3KMT2ADRD2 | |
| Trifluoroacetic Acid SCHEMBL1021467 | 0.87 | SLC2A1 (0.48) | SLC2A1DCUN1D1UBE2MACKR3KMT2A | |
| Trifluoroacetic Acid SCHEMBL1019196 | 0.86 | SMN1; SMN2 (0.40) | SLC2A1DCUN1D1UBE2MACKR3KMT2A | |
| SCHEMBL12954974 | 0.84 | DRD2 (0.47) | DCUN1D1UBE2MACKR3KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL1074147 | 0.83 | ACKR3 (0.46) | DCUN1D1UBE2MACKR3KMT2ADRD2 | |
| SCHEMBL1017953 | 0.83 | DCUN1D1 (0.41) | DCUN1D1UBE2MACKR3KMT2ADRD2 | |
| SCHEMBL13663359 | 0.82 | KMT2A (0.41) | DCUN1D1UBE2MACKR3KMT2ADRD2 | |
| SCHEMBL12954826 | 0.82 | ACKR3 (0.45) | DCUN1D1UBE2MACKR3KMT2ADRD2 | |
| SCHEMBL12955054 | 0.81 | USP30 (0.41) | ACKR3KMT2AALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314091-B2 | N-benzyl,N'-arylcarbonylpiperazine derivatives | MSD OSS B.V. (NL) | 2012-11-20 | — | — | US | disclosed |
| EP-2190827-B1 | N-BENZYL-N'-ARYLCARBONYLPIPERAZINE DERIVATIVES AS LXR MODULATORS | ORGANON NV (NL) | 2011-01-12 | — | — | EP | disclosed |
| US-20090264416-A1 | N-BENZYL,N'-ARYLCARBONYLPIPERAZINE DERIVATIVES | N.V. ORGANON AND PHARMACOPEIA, INC. | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264416-A1 | N-BENZYL,N'-ARYLCARBONYLPIPERAZINE DERIVATIVES | NPC1L1, NPC1, ABCB11 | SLC2A1 233/4885DCUN1D1 4520/4885UBE2M 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.