SCHEMBL10179744

SCHEMBL10179744

O=C(Oc1c(F)ccc(F)c1F)C(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
BCHE P06276 1/20 0.31
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10181456 0.85 CES2 (0.42) CES2CES1BCHE
SCHEMBL10179857 0.83 KMT2A (0.41) CES2CES1BCHE
SCHEMBL10179556 0.80 CES2 (0.38) CES2CES1
SCHEMBL1401784 0.78 TSHR (0.33)
SCHEMBL10180361 0.76 CES2 (0.35) CES2CES1
SCHEMBL10180796 0.75 CES2 (0.40) CES2CES1BCHE
SCHEMBL17552763 0.74 RIPK1 (0.46) CES2CES1
SCHEMBL10181495 0.73 CES2 (0.38) CES2CES1
SCHEMBL2003057 0.72 CES2 (0.45) CES2CES1BCHE
SCHEMBL10180733 0.72 CES2 (0.39) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed