SCHEMBL10179985

SCHEMBL10179985

C=C(C)C(=O)OCCC12CC3CC(CC(C3)C1CCC#N)C2

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
THRB P10828 1/20 0.31
TSHR P16473 2/20 0.31
ALDH1A1 P00352 2/20 0.30
MAPT P10636 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10180550 0.93 TSHR (0.32) MEN1KMT2ATHRBTSHR
SCHEMBL10179724 0.88 MEN1 (0.33) MEN1KMT2ATHRBTSHRALDH1A1
SCHEMBL550030 0.86 MEN1 (0.34) MEN1KMT2ATHRBTSHRALDH1A1
SCHEMBL10233144 0.84 MEN1 (0.33) MEN1KMT2AALDH1A1MAPTATM
SCHEMBL10181507 0.79
SCHEMBL10233092 0.74 MEN1 (0.39) MEN1KMT2ATHRBTSHRALDH1A1
SCHEMBL549925 0.73 ALDH1A1 (0.36) MEN1KMT2ATHRBTSHRALDH1A1
SCHEMBL20920211 0.73 ALDH1A1 (0.36) MEN1KMT2ATHRBTSHRALDH1A1
SCHEMBL5001405 0.72 MEN1 (0.56) MEN1KMT2ATHRBTSHRALDH1A1
SCHEMBL20920212 0.70 ALDH1A1 (0.37) MEN1KMT2ATHRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8802349-B2 Actinic ray-sensitive or radiation-sensitive resin composition and resist film and pattern forming method using the composition FUJIFILM CORPORATION (JP) 2014-08-12 US disclosed
US-8802349-B2 Actinic ray-sensitive or radiation-sensitive resin composition and resist film and pattern forming method using the composition FUJIFILM CORPORATION (JP) 2014-08-12 US disclosed
US-20120015301-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST FILM AND PATTERN FORMING METHOD USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2012-01-19 US disclosed