SCHEMBL10180550

SCHEMBL10180550

C=C(C)C(=O)OCCC12CC3CC(CC(C3)C1CCCC#N)C2

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10179985 0.93 MEN1 (0.32) TSHRMEN1KMT2ATHRB
SCHEMBL10179724 0.86 MEN1 (0.33) TSHRMEN1KMT2ATHRB
SCHEMBL550030 0.84 MEN1 (0.34) TSHRMEN1KMT2ATHRB
SCHEMBL10233144 0.83 MEN1 (0.33) MEN1KMT2A
SCHEMBL10181507 0.77
SCHEMBL10233092 0.72 MEN1 (0.39) TSHRMEN1KMT2ATHRB
SCHEMBL549925 0.71 ALDH1A1 (0.36) TSHRMEN1KMT2ATHRB
SCHEMBL20920211 0.71 ALDH1A1 (0.36) TSHRMEN1KMT2ATHRB
SCHEMBL5001405 0.70 MEN1 (0.56) TSHRMEN1KMT2ATHRB
SCHEMBL530161 0.69 TSHR (0.56) TSHRMEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8802349-B2 Actinic ray-sensitive or radiation-sensitive resin composition and resist film and pattern forming method using the composition FUJIFILM CORPORATION (JP) 2014-08-12 US disclosed
US-8802349-B2 Actinic ray-sensitive or radiation-sensitive resin composition and resist film and pattern forming method using the composition FUJIFILM CORPORATION (JP) 2014-08-12 US disclosed
US-20120015301-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST FILM AND PATTERN FORMING METHOD USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2012-01-19 US disclosed