Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 14/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3065086 | 0.99 | STAT3 (0.44) | STAT3SCN9APIK3CAPRKAA2 | |
| SCHEMBL3057097 | 0.86 | STAT3 (0.39) | STAT3SCN9A | |
| SCHEMBL3065457 | 0.84 | STAT3 (0.38) | STAT3 | |
| SCHEMBL3056039 | 0.84 | STAT3 (0.38) | STAT3 | |
| SCHEMBL3064149 | 0.83 | STAT3 (0.37) | STAT3 | |
| Bromide SCHEMBL3045909 | 0.83 | STAT3 (0.54) | STAT3SCN9APIK3CAPRKAA2 | |
| SCHEMBL10180856 | 0.79 | HRH3 (0.39) | STAT3 | |
| SCHEMBL10180502 | 0.79 | STAT3 (0.53) | STAT3SCN9APIK3CAPRKAA2 | |
| Bromide SCHEMBL3060752 | 0.79 | HRH3 (0.39) | STAT3 | |
| SCHEMBL3066800 | 0.78 | SCN9A (0.57) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207773-B1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMA CO LTD (JP) | 2012-07-11 | — | — | EP | disclosed |