Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | STAT3 | P40763 | 11/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3060752 | 0.99 | HRH3 (0.39) | HRH3STAT3MEN1KMT2ASLC6A2 | |
| SCHEMBL3064149 | 0.90 | STAT3 (0.37) | HRH3STAT3MEN1KMT2A | |
| SCHEMBL3065457 | 0.89 | STAT3 (0.38) | HRH3STAT3MEN1KMT2A | |
| SCHEMBL3057097 | 0.85 | STAT3 (0.39) | HRH3STAT3MEN1KMT2A | |
| Bromide SCHEMBL3062614 | 0.84 | STAT3 (0.46) | STAT3 | |
| SCHEMBL3056039 | 0.83 | STAT3 (0.38) | HRH3STAT3MEN1KMT2A | |
| SCHEMBL3046919 | 0.80 | SCN9A (0.43) | HRH3STAT3MEN1KMT2A | |
| SCHEMBL10180503 | 0.79 | STAT3 (0.45) | STAT3 | |
| SCHEMBL10180858 | 0.79 | MEN1 (0.48) | STAT3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL3057678 | 0.79 | HRH3 (0.41) | HRH3STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207773-B1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMA CO LTD (JP) | 2012-07-11 | — | — | EP | disclosed |