Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3729976 | 0.90 | CA2 (0.52) | HSD17B10KDM4ESMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL3729975 | 0.90 | CA2 (0.52) | HSD17B10KDM4ESMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL3746257 | 0.81 | MAPK1 (0.55) | HSD17B10ALDH1A1TSHRMAPK1CA12 | |
| SCHEMBL3746255 | 0.81 | MAPK1 (0.55) | HSD17B10ALDH1A1TSHRMAPK1CA12 | |
| SCHEMBL3738266 | 0.75 | CA2 (0.63) | GFERHSD17B10KDM4EALDH1A1CA12 | |
| SCHEMBL3738270 | 0.75 | CA2 (0.63) | GFERHSD17B10KDM4EALDH1A1CA12 | |
| SCHEMBL3735058 | 0.73 | CA2 (0.54) | ALDH1A1TSHRMAPK1CA12CA1 | |
| SCHEMBL3735061 | 0.73 | CA2 (0.54) | ALDH1A1TSHRMAPK1CA12CA1 | |
| SCHEMBL3735047 | 0.72 | CA2 (0.55) | CA12CA1CA2CA3CA4 | |
| SCHEMBL3743439 | 0.70 | ALOX15 (0.53) | TSHRCA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468734-A1 | Development of molecular imaging probes for carbonic anhydrase-IX using click chemistry | Siemens Medical Solutions USA, Inc. (US) | 2012-06-27 | — | — | EP | disclosed |